STRATIFYING THE RISK OF ADVERSE CARDIOVASCULAREVENTS IN ACUTE MYOCARDIAL INFARCTIONWITH ST-SEGMENT ELEVATION

Abstract

Objective: The aim of our study was to evaluate the prognostic role of β-APM in patients for
myocardial infarction with segment elevation ST (STEMI).
Materials and Methods: In the present research, carried out the study of β-adrenoreception
erythrocyte membranes (β-APM) in 81 patients with myocardial infarction with ST-segment elevation
with a different course of the disease. β-adrenoreactivity of organism was determined by the value of βAPM using the diagnostic reagent kit "ARM-agate" (LLC "Agat-Med", Moscow). All patients were divided
into 2 groups. 1st group consisted of 49 patients who did not have complications, both in hospital period
and post it. In the 2nd group consisted of the 32 patients with different complications of the
cardiovascular system.
Results: In patients with STEMI average value of β-APM in the 2 groups was 29,9 ±1,24 The
average value of β-APM in the first group was significantly 34,07 ±1,6 (p<0.05). In the 2 nd group, the
mean value of β-APM was 23,5 ±1,31 (p<0.05), against 19,2 ±2,3 (p<0.05) in the control group,
respectively. The findings led to the conclusion that the initial value of β-APM with STEMI may have
prognostic value, within a year of onset. In patients with STEMI at a low β-APM were highly probability
to develop complications. With high rates of β-APM in contrast, it is a favorable prognostic sign.
Conclusions: Thus, we suggest that in patients of myocardial infarction with ST-segment elevation
at the β-APM is less than 20 is a poor prognostic indicator in the development of cardiovascular
complications.