PROGNOSTIC VALUE OF RENAL DYSFUNCTION IN PATIENTSWITH ISCHEMIC HEART DISEASEAFTER MYOCARDIAL REVASCULARIZATION

Abstract

The Aim. Study about disturbance of renal dysfunction (RD) and its prognostic significance in patients with ischemic
heart disease (IHD) who have undergone myocardial revascularization.
Materials and methods. 675 patients from cardiology department were analyzed by retrospective analysis of history of
the disease, in which there was a transfer of percutaneous coronary intervention (PCI) and / or coronary artery bypass
surgery. The prevalence of risk factors, features of coronary blood flow, structural and functional changes of the heart were
studied.

Statistical processing was performed by SPSS 20.0: descriptive statistics, Mann-Whitney U-test for independent
samples, Chi-square, single-factor and multifactorial logistic regression. Differences between the compared variables were
considered significant at p<0.05.
Results. PD was detectedin 163 (24,1%) patients, their age was significantly older (p<0,001). The main factors of
cardiovascular risk were: arterial hypertension (AH), diabetes mellitus (DM), myocardial infarction (MI) and acute violation of
cerebral circulation (AVCC). In 14,2% of cases death was detected from all causes, in the group with PD, significantly more
than without (21,5% vs. 11,9%, p=0,002). As a result of a multifactor regression analysis, factors affecting the adverse
course of the disease were established: age (p<0,001), creatinine level (p=0,026), EF LV (p<0,001).
Conclusion. Renal dysfunction is one of the main independent predictors of adverse outcome in ischemic heart
diseasein patients after myocardial revascularization.