РREVALENCE AND IMPACT ON LIFE QUALITYOF DERMATOPHYTOSIS IN THE WORLD

Abstract

Background: In dermatological structure of morbidity, fungal diseases take the second place after pyoderma and
account for up to 42% of skin diseases. The problem of dermatomycosis is of great relevance due to the variety of
transmission routes of pathogens and their high resistance in the external environment, changes in the immune response of
human body.
Aim: Analysis of scientific information on incidence and species composition of causative agents of dermatomycoses in
different regions of the world, and their influence on quality of life.

Search strategy: The search for scientific publications was conducted in databases PubMed, Elsiever, Medline,
GoogleScholar
Results: About 25% of the world's population suffer from dermatophytes, and Trichophyton rubrum is the main causative
agent. The predominance of T. violaceum is observed in the north and east of Africa, and T. Sudanense and M. audouinii
predominate in the western and central regions of Africa. In India, the leading causative agents are Trichophyton
mentagrophytes and T. rubrum. In Europe, onychomycosis is most often caused by T. rubrum and T. interdigitale, tinea
capitis is caused by M. audouinii, T. tonsurans, T. violaceum, T. soudanense and M. sanis. With persistent and relapsing
dermatophytes, an extremely large and very large impact on life quality was revealed, affecting not only physiological
aspects of patients' lives, but also their emotional and social well-being. In patients with lesions in the inguinal folds and
buttocks, the quality of life worsened to a greater extent than in other sites.
Conclusion: Trichophyton rubrum is the most common pathogen, although the frequency of infections caused by T.
interdigitale and T. mentagrophytes is increasing. A significant influence of persistent and resistant forms of dermatomycoses
on life quality has been revealed.