TUBERCULOSIS MULTIDRUG-RESISTANT.(LITERATURE REVIEWS)

Abstract

Introduction. Drug-resistant tuberculosis is a global challenge of our time. According to WHO, each
year half a million new cases of MDR-TB. Tuberculosis drug resistance is characterized by high
mortality rates, while the complexity and high cost of its treatment.
The aim of the study was to examine the problems of MDR-TB worldwide in the CIS countries, in
Kazakhstan.
Research methods. This review considers the main problem of MDR-TB, which have been studied
in the research for the period from 1999 to 2016. The criterion for inclusion in the publication of the
review was to study all over the world, in the CIS countries, in Kazakhstan. 250 publications on the topic
of MDR-TB, of which meet the main goal of our study 51 publications were found.
Results. Review of the literature showed that the tuberculosis as a socially mediated diseases remains
a serious problem in Kazakhstan and in the whole world, ranking first in the structure of causes of death
from infectious diseases today. One of the main reasons for the low efficacy and the high death rate from
tuberculosis was widespread multidrug resistance of Mycobacterium tuberculosis to anti-TB drugs.
Conclusions. The problem MBT drug resistance poses a great threat to TB control, and is the
subject of increased controls on global health security.