RETROSPECTIVE EVALUATION OF PATIENTS DIAGNOSED WITH ACUTE CORONARY SYNDROME

Abstract

Introduction. Early diagnosis and treatment of acute coronary syndromes as a life threatening disease group is crucial
in emergency departments. Acute coronary syndrome (ACS) term is used to define a disease spectrum including unstable
angina pectoris, ST-segment elevation myocardial infarction (STEMI), and non-ST-segment elevation myocardial infarction
(NSTEMI).
The objective of this study was to compare unstable angina pectoris (USAP), ST-segment elevation myocardial
infarction (STEMI), and non-ST-segment elevation myocardial infarction (NSTEMI) groups in terms of the blood parameters
such as mean platelet volume (MPV), red cell distribution width (RDW), C-reactive protein (CRP), neutrophil-to-lymphocyte
and platelet-to lymphocyte ratios; and data such as patients’ sociodemographic and clinical characteristics, time and day of
the admission, diagnosis of the admission to coronary intensive care unit, ECG findings, and comorbidity, and to investigate
the relationship between them.
Materials and methods: A total of 659 patients included in the study. Patients were divided into 3 groups according to
the diagnosis of admission as STEMI, NSTEMI, and USAP groups. Patients’ age, gender, complaints of presentation to
emergency department (ED), presumed diagnosis, hemogram, MPV, RDW, CRP, troponin, neutrophil-to-lymphocyte, and
platelet-to-lymphocyte ratios were evaluated.
Results: The patients were mostly male (71.8%), the most common age range was 45-59 years (40.2%). Troponin value
was significantly lower in USAP group compared to STEMI and NSTEMI group (p<0.05). The median RDW value was lower
in the STEMI group than NSTEMI and USAP groups (p<0.05). Neutrophil-to lymphocyte ratio was significantly lower in USAP
compared to STEMI and NSTEMI groups (p<0.05). No significant difference was found between the three groups in terms of
platelet-to-lymphocyte ratio (p>0.05).
Conclusion: In this study, we evaluated data of ACS patients who presented to the emergency department. We believe
that such data will be guiding diagnosis and treatment of patients with ACS.