MICROBIOLOGICAL INDICATORS OF OUTPATIENTS’UNCOMPLICATED URINARY TRACT INFECTION

Abstract

Introduction: Urinary tract infections are among the most common infections diagnosed in both outpatient and
hospitalized patients, but the study of the bacterial structure and resistance of pathogens is not so widely studied at the
outpatient stage.
We aimed to study microbiologic landscape and antibiotic susceptibility of strains isolated from outpatient’s urine
samples.
Materials and methods: A prospective microbiological study of bacterial landscape and antibiotic susceptibility of strains
isolated from 202 outpatients’ urine samples based on Microbiology Laboratory of National Scientific Medical Research
Center during September 2019 to October 2020. Identification of isolates were performed by Vitek-2 automated system. Statistical processing of the obtained data was carried out using Microsoft Excel, the average value, the error of the
mean were determined, dynamic changes were determined by the method of linear regression. Differences in mean values
were considered statistically significant at p<0.05
Results: During study period, 158 clinical samples were included, 75 strains were isolated; of them and the most
frequently isolated microorganisms was E.coli - 76%. Antibiotic susceptibility of E.coli strains was to ampicillin – 43.8%, to III
generation cephalosporins – 66.6%, to quinolones – 68.4% and to aminoglycosides – 77.1%. The highest sensitivity is
observed to nitrofurantoin 94.7% and co-trimoxazole 89.4%.
Conclusion: Based on our results the most frequently pathogens of outpatients’ uncomplicated urinary tract infection
was E.coli with high level of susceptibility to nitrofurantoin 94.7% and co-trimoxazole 89.4%