GENOMIC INSTABILITY IN ONCOCYTIC FOLLICULAR ADENOMA OF THE THYROID
DOI:
https://doi.org/10.34689/rn025b94Keywords:
adenoma , oncocytic cells , tumor , nuclear fociAbstract
Oncocytic follicular adenomas of the thyroid are neoplasmas of follicular cell origin that are predominantly composed of
large polygonal cells with eosinophilic and granular cytoplasm. However, the pathological characteristics of these tumors are
the largely unexplored. The diagnosis of malignancy is reliably based on histological evidence of capsular invasion or
vascular invasion, extrathyroidal local tissue invasion, and nodal or distant metastasis. Both the initiation and progression of
cancer can be caused by an accumulation of genetic mutations that can induce genomic instability.
References
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adenoma of the thyroid // Nauka i Zdravookhranenie [Science & Healthcare]. 2022, (Vol.24) 4, pp. 133-136. doi
10.34689/SH.2022.24.4.017
Козыкенова Ж.У., Мадиева М.Р., Шалгимбаева Г.С., Мусажанова Ж.Б. Геномная нестабильность при
онкоцитарной фолликулярной аденоме щитовидной железы // Наука и Здравоохранение. 2022. 4(Т.24). С. 133-136.
doi 10.34689/SH.2022.24.4.017
Қозыкенова Ж.У., Мадиева М.Р., Шалгимбаева Г.С., Мусажанова Ж.Б. Қалқанша безі фолликулярлық ісіктері
онкоцитарлық түрінің геномдық тұрақсыздығы // Ғылым және Денсаулық сақтау. 2022. 4 (Т.24). Б. 133-136. Doi
10.34689/SH.2022.24.4.017
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Copyright (c) 2026 Жанна Козыкенова, Мадина Мадиева, Гульзира Шалгимбаева, Жанна Мусажанова (Автор)
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