THE IMPACT OF ANTIEPILEPTIC DRUGS ON COGNITIVE FUNCTIONS IN EPILEPSY. LITERATURE REVIEW
DOI:
https://doi.org/10.34689/seqkz325Keywords:
epilepsy , antiepileptic drugs , cognitive functions , neuropsychological testing , EpiTrackAbstract
Background: Epilepsy affects more than 70 million people worldwide. Antiepileptic drugs (AEDs) represent the basis of
treatment; however, 30-40% of patients develop drug resistance. In addition, cognitive impairments are frequently observed
in the context of polytherapy.
Objective: To analyze the literature on the effects of antiepileptic drugs on cognitive functions assessed using EpiTrack
tool in patients with epilepsy.
Materials and methods: A literature search was performed in PubMed, Scopus, and Google Scholar databases. Eligible
studies included full-text publications in English and Russian over the past 15 years that investigated the effect of
antiepileptic drugs on cognitive functions.
Results: A total of 1,066 records were identified in the PubMed, Scopus, and Google Scholar databases. After
screening, 5 full-text articles met the inclusion criteria and were analyzed.
Conclusions: The review highlights that the cognitive impact of AEDs depends on both the quantity and the
pharmacological profile of the drugs used.
References
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Бекенова Н., Касиева Б., Айткалиев А., Сулейменова А., Вощенкова Т., Досов М., Жумабаева Г. Влияние
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Бекенова Н., Касиева Б., Айткалиев А., Сулейменова А., Вощенкова Т., Досов М., Жумабаева Г. Эпилепсия
кезіндегі когнитивтік функцияларға эпилепсияға қарсы дәрілердің әсері. Әдебиеттік шолу // Ғылым және Денсаулық
сақтау. 2025. Vol.27 (5), Б. 244-250. doi 10.34689/SH.2025.27.5.028
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Copyright (c) 2025 Назира Бекенова, Балжан Касиева, Алишер Айткалиев, Акмарал Сулейменова, Тамара Вощенкова, Мухит Досов, Гулдана Жумабаева (Автор)
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