ANTIBIOTIC RESISTANCE SURVEILLANCE IN A PEDIATRIC CARDIAC SURGERY

Abstract

Background. The aim of this study was to identify etiological organisms and antibiotic resistance rates of bacterial
infection in Department of pediatric cardiac surgery.
Methods. Our database consisted of 2816 consecutive samples from pediatric patients who underwent cardiac surgery
between January 2011 and December 2019 at a single center. Identification of isolates and antibiotic susceptibility testing
were performed by Vitek-2 automated system.
Results: The most frequently isolated microorganisms in our Department of pediatric cardiac surgery were as follows:
Psedomonas aeruginosa 19.7%, Klebsiella pneumoniae 16%, Staphylococcus aureus 13.2%, and Acinetobacter baumannii
8.8%. During study period there is tendency increasing the percentage of detection Ps.aeruginosa from 16.1% to 30.2%
(p=0.048) and K.pneumoniae from 7.5% to 19.3% (p=0.014). There are tendency of increasing resistance to 3rd generation
cephalosporins, carbapenems and quinolones.
Conclusion. Based on our results, we report that respiratory tract infection was found to be the most common site for
bacterial infection and P.aeruginosa and K. pneumoniae were the most frequent pathogens with high level of resistance. Our
findings are posing necessitates for improvement preventive measures, including microbiological monitoring, good hygiene,
and well-designed hospital infection control strategy.