PATHOPHYSIOLOGICAL CHARACTERISTICS OF THE CHRONIC POSTTRAUMATIC OSTEOMYELITIS AND PERIPROSTHETIC INFECTION

Abstract

In this review article, two complex problems of medicine are considered - chronic post-traumatic osteomyelitis and
periprosthetic infection. During the review, the features of the pathophysiological course of these formidable diseases are
described in detail. Along with the description of the pathophysiology of these processes, the main issues of modern
methods of treating them are also addressed.
To aim of the study was: to study the features of the pathophysiological course of chronic post-traumatic osteomyelitis
and periprosthetic infection, as well as modern methods of treating these diseases.
Search strategy. To achieve the goal of the study, we conducted an analysis of foreign and domestic literary sources.
The search for sources was carried out using the Internet resources PubMed, Medline, Cochrane Library in the interval
between 2009-2019. Inclusion criteria were: articles in the period 2009-2019 which addressed issues of chronic
osteomyelitis, purulent bone infections, as well as periprosthetic infections. The exclusion criteria were: all articles that went beyond the time frame of the search, as well as articles that addressed issues of infection of soft tissues and were not
involved in endoprosthetics.
Results. The presented review article describes two problems - chronic post-traumatic osteomyelitis and periprosthetic
infection. The main strains that cause these two diseases or are most often sown during microbiological studies are
described in detail, and the problem of biofilm formation when using metal structures is described, which has recently been a
big problem for practitioners.
Conclusion. The presented review article will be interesting for doctors closely involved in this issue, as well as for
specialists in related industries.