BACTERIAL VAGINOSIS AND DESQUAMATIVE INFLAMMATORY VAGINITIS: CHOICE OF AN EFFECTIVE THERAPY METHOD. REVIEW

Abstract

Relevance. Bacterial vaginosis and desquamative inflammatory vaginitis are one of the most common causes of
patients' visits to gynecologists, primary care providers and emergency care centers. However, many women leave without a
clear diagnosis or experience recurring symptoms despite treatment. The three most common etiologies of vaginitis are
trichomonas, bacterial vaginosis and vulvovaginal candidiasis, which account for about 70% of cases. The remaining 30%
may be related to other causes of vaginitis, including atrophic vaginitis, desquamative inflammatory vaginitis and erosive
vaginal disease.
Aim of this review is to describe the common causes bacterial vaginosis and desquamative inflammatory vaginitis in
order to increase the likelihood of accurate diagnosis, as well as effective and efficient therapy.
Search strategy. The study examined full-text publications in English and Russian, which are devoted epidemiology and
treatment of bacterial vaginosis and desquamative inflammatory vaginitis. In the process of searching for literature, the
following search engines were used: Pubmed, Web of science, Cyberleninka, Google Scholar by keywords. The time period
was designated 2012-2022. 282 publications were identified on this topic. Of these, 52 publications corresponded to the
purpose of our study. Inclusion criteria: Publications of the level of evidence A, B: meta-analyses, systematic reviews, cohort
and cross-sectional studies. Exclusion criteria: summary reports, newspaper articles and personal messages.
Results and conclusions. As a result of numerous studies, it has been established that the vaginal pathway for the
treatment of bacterial vaginosis and desquamative inflammatory vaginitis is not inferior in effectiveness to oral therapy. In
addition, the vaginal route of treatment is more preferable due to the lower likelihood of adverse reactions.More research is
needed to better characterize the cause and treatment of vaginosis and vaginitis. Some studies have shown an improvement
in symptoms with the use of topical clindamycin or steroids; however, the ideal duration of treatment and the superiority of
one remedy over the other have not been established.